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KMID : 0359320190590020089
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Korean Journal of Veterinary Research
2019 Volume.59 No. 2 p.89 ~ p.96
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Prevalence and molecular characterization of novel recombinant enterovirus G isolates in Jeju Province of South Korea
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Jeon Ji-Hyun
Lee Chang-Hee
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Abstract
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Enterovirus species G (EV-G) is highly diverse, and is ubiquitous in pig populations, usually without diarrhea. The presentstudy aimed to investigate the presence of novel EV-G recombinants with the torovirus papain-like cysteine protease (PLCP) in Jejupig herds. EV-G1-PLCP mono-infections were most prevalent in diarrheic weaned piglets. The PLCP genes of the Jeju isolates variedin size and junction sequences, and were greatly heterogeneous, with 77.0?90.7% homology amongst all recombinants. Our resultssuggest that the exogenous PLCP gene has undergone continuous rapid mutation in the individual EV-G genomes following crossorderrecombination, thereby causing clinical disease in swine.
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KEYWORD
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cross-order recombination, EV-G, PLCP, porcine diarrhea, torovirus
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